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متابعة

What are the Vitamin K Dependent Coagulation Factors ?

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تم إضافة السؤال من قبل Mozfar Idrees , Medical Laboratory Director , Asia Polyclinic
تاريخ النشر: 2014/11/20
bahjat alabou houseen
من قبل bahjat alabou houseen , clinical hematologist , KING ABDULAZIZ SPECIALIZED HOSPITAL IN TAIF

Vit K is essential for activity of several carboxylase enzymes within the hepatic cells,and therefore is necessary for the activation of coagulation factors VII,IX,X,II.These factors contain carboxyglutamic acid,which is carboxylated by gamma-glutamyl carboxylase. Vit K is the active coenzyme in this process,providing energy for the reaction through oxidation,after carboxylation,these proteins gain affinity for the negatively charged phospholipids on the surface of platelets and promote coagulation.

Hisham morsi
من قبل Hisham morsi , clinical Pathology/ Hematology/ HAAD Licensed , Assist Prof. University of Cairo, National Cancer Institute

Factors are10,9,7,2. To be remembered easily it resembles year1972

Biplab Bhattarai
من قبل Biplab Bhattarai , Laborotary Technician , Manmohan memorial medical college & Teaching Hospital

Vit k dependent factors are II,VII, IX, X.

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