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Adobe Muse you didn't worry any more on html and css or photoshop and illsutrator but .... must be Photoshop CC or Illustrator CC or else you can't generate a css on layer or an option to copy the css and paste it on adobe edge code... creating a website in there is100 percent responsive and its like creating an advertisement that no need to type html and css... good luck...
I think same tools can be used to design web designing, but you need to change the frame of mind to design for web, some of the differences are mentioned below
I use Adobe Muse on a daily basis a my web designing program.Widgets, CSS and social platform tools can be easily added onto your pages.Although measurements will be in pixels only.