Can anyone tell me how site-to-site vpn will work between cisco asa and chechpoint?

Hi,

     I have configured S2S VPN on different Checkpoint Models like R65, R70, R71, R75 using the GUI mode. Don't think there is much of a difference in the way S2S VPN is going to work as its going to run on IPSEC Protocols which is a Market/Open Standards, the Phase1 and Phase2 formations are going to be similar as they are when you configure between Cisco-Cisco Devices. 

Only difference will be the way you setup your VPN Configurations. Hope this helps!!!