Your question is a little bit unclear. Might be this article help you: http://docs.joomla.org/How_do_you_assign_a_template_to_a_specific_page
Can you please explain your question a little bit so that people could answer more specifically?
As per my understanding, you want to create multiple layouts in a single template.
If yes follows the steps of following links:
http://www.own-it.nl/creating-different-styles-for-your-joomla-template
Hope this will help you.
Thanks,
Abrar