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Why is Clostridium Botulinum considered a biological weapon?

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تم إضافة السؤال من قبل Sara Rawass , Secondary Sciences teacher , Doha Academy
تاريخ النشر: 2017/06/12
Hamid K MD
من قبل Hamid K MD , Biology academic teacher , GOOD SHEPHERD ENGLISH SCHOOL

Clostridium botulinum causes the disease called botulism by producing most potent toxins known to mankind.But one of the most fascinating aspects of anaerobic spore-former Gram positive bacillus is treatment of neurological disorders.It has become the first biological toxin which is licensed as drug for treatment of human diseases.

Dharmajan Divakaran DipOSH
من قبل Dharmajan Divakaran DipOSH , Safety Engineer , Honeywell Kuwait K.S.C

Extreme potency and lethality of botulinmum, its considered a biological weapon.  A single gram of crystalline toxin, evenly dispersed and inhaled, would kill more than 1 million people, although technical factors would make such dissemination difficult.

An aerosolized or foodborne botulinum toxin weapon would cause acute symmetric, descending flaccid paralysis with prominent bulbar plasies such as diplopia, dysarthria, dysphonia, and dysphagia that would typically present 12 to 72 hours after exposure.

Selim TURKI
من قبل Selim TURKI , Laboratory Technician , Public hospital AZIZA OTHMANA Tunis

Because it's the main cause for botulism which is extremely a very dangerous disease caused by clostrodium itself who produce toxins into the human body that can cause paralysis.

Shah Faisal
من قبل Shah Faisal , research assistant , agriculture research institute swat

The botulinum toxin can cause a severe flaccid paralytic disease in humans and other animals[2] and is the most potent toxin known to mankind, natural or synthetic, with a lethal dose of 1.3–2.1 ng/kg in humans.

Mohamed Khalil Hosseini saleh
من قبل Mohamed Khalil Hosseini saleh , Quality assurance microbiology lab supervisor , Foodlover

Botulinum toxin, one of the most toxic poisons known, is derived from the spore-forming bacteria Clostridium botulinum.

It is listed as "the most toxic substance known."

2 It is estimated that a single gram of pure crystalline toxin, evenly dispersed and inhaled, could kill as many as one million people.

3 However, such a dissemination would be technically unfeasible, since an effective mechanism for producing a large aerosol of botulinum has not been successfully developed.

Botulinum toxin can be absorbed through the gastrointestinal or respiratory tracts; however, it is not absorbed by intact skin. The estimated lethal dose for a 91-kg (200-pound) person is 0.9–1.2 micrograms per kilogram by inhalation, and approximately 90 micrograms per kilogram by oral ingestion.4 Symptoms of botulinum toxin poisoning can occur within as little as two hours of exposure, or as late as eight days after.

BOUAZIZI  MARWA
من قبل BOUAZIZI MARWA , Pharmacist Assistant , pharmacy of Lessouda

the toxin produced by Clostridium Botulinum is a very rare one that causes mainly paralysis and most of the world wide population is not vaccinated and protected against it . a very small quantity can kill a large number of people . that why its considered as a biological weapon

Husamuddin Alkhalil
من قبل Husamuddin Alkhalil , Head of Science dept. , Leaders acadimy

because it is poisining cells as takes oxygen from them

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