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What are the medicines that should not be taken together with other medicines?

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Question added by Ayman Khalil
Date Posted: 2015/06/04
Zoheb Dholakia AIII
by Zoheb Dholakia AIII , Deputy Manager Operations , Aditya Birla Health Insurance Co. Ltd.

There are plenty of medicines which are not taken simultaneously mainly due to the effect one has over the other in absorption, distribution, metabolism and excretion / elimination (ADME) . You can find example in answer of Mr. Nasir Hussain above. The interference of one of them on other may increase or decrease ADME and thus have bad effects on body. Colestipol reduces absorption of many drugs thus it is taken2 hours before or4 hours after plenty of other drugs.

Nasir Hussain
by Nasir Hussain , Sales And Marketing Manager , Pakistan Pharmaceutical Products Pvt. Ltd.

There is long range of drug that should not be used along with other drug to avoid possible drug-drug interactions. A few of them are listed below:

 

 

1- Acid Reducers H2 Receptor Antagonists(drugs that prevent or relieve heartburn associated with acid indigestion and sour stomach)

E.g., Cimetidine, has interaction with ..........

·         theophylline (oral asthma drug), warfarin (blood thinning drug), or phenytoin (seizure drug)

 

2- Antacids(drugs for relief of acid indigestion, heartburn, and/or sour stomach)

has interaction with ..........

·         milk or milk products if the product contains more than5 grams lactose in a maximum daily dose

 

3-Antiemetics(drugs for prevention or treatment of nausea, vomiting, or dizziness associated with motion sickness)

has interaction with ..........

·         sedatives or tranquilizers

·         alcoholic beverages

 

4- Antihistamines(drugs that temporarily relieve runny nose or reduce sneezing, itching of the nose or throat, and itchy watery eyes due to hay fever or other upper respiratory problems)

has interaction with ..........

·         sedatives or tranquilizers

·         Anti-hypertensives, Anti depressants

·         alcoholic beverages

 

5- Antitussives Cough Medicine(drugs that temporarily reduce cough due to minor throat and bronchial irritation as may occur with a cold)

has interaction with ..........

·         sedatives or tranquilizers

 

6- Laxatives(drugs for the temporary relief of constipation)

has interaction with ..........

·         medicines that contains phosphates, potassium, or magnesium

 

 

7- Nasal Decongestants(drugs for the temporary relief of nasal congestion due to a cold, hay fever, or other upper respiratory allergies)

has interaction with ..........

·         Anti-hypertensives, Anti diabetics

·         thyroid medicines, Alpha blockers (for prostate enlargement)

 

8- Nighttime Sleep Aids (drugs for relief of occasional sleeplessness)

has interaction with ..........

·         Other sedatives or tranquilizers

·         Alpha blockers (for prostate enlargement)

·         alcoholic beverages

 

9- Pain Relievers(drugs for the temporary relief of minor body aches, pains, and headaches)

has interaction with ..........

·         alcoholic beverages

(The following ingredients are found in different OTC pain relievers: acetaminophen, aspirin, ibuprofen, ketoprofen, magnesium salicylate, and naproxen. It is important to read the label of pain reliever products to learn about different drug interaction warnings for each ingredient.)

 

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