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I had to manage the same situation many times and solution i explored and implemented are as follows.
1. Nominate the characters, pair up most relevant together and make candidates opposite to each other at middle rows of the class and rest of all surrounded them beside wall.
2. Let the audience sitting at theirs seats and asking the drama character to stand up and perform.
3. Don't forget to make few changes in your drama as well so that your characters need not to move much