Can a good cv make you qualified for a job even if you can not defend it?

Not always.

The recruiters do look for organisational fit prior to considering the candidate.

Every workplace has its culture and a CV is only to get you to the position. Hence, defending a job after getting recruited, needs learning, flexibility and adaptation on the part of the hired professional. A smart worker continues to work on these aspects and a good manager will not fail to observe the adaptation capabilities of the candidate. 

CV can gives you lots of interviews but none will hire you