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Primavera P6 is much more powerful than that of MSP.
There is a great article if you want you can read it from here,
MSP runs on local, just like excel sheet where all the tasks and resources have been loaded, MSP allows any user to open a specific project provided MSP file and MSP system is available.
No Dashboards, where one cannot see the progress of the portfolios/programs.
Primavera P6 EPPM runs both on system(when installed) and can be accessible from cloud , where project access to each users would be defined.
Has dashboards to have snap shot of all the protfolio of projects at one place.
And Differences many more between, when we started working in deeper....