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yes we can interface MATLAB with arduino by serial communication.
WE CAN INTERFACE BY SERIAL AS WELL AS TO PARALLEL CONVERSION SYSTEM
Matlab is Considered as a Development Environment so the key in your communication is the make file you got either you make it manually or you let the IDE do it for you, so it is a;; about the make file
Of Course we could interface Matlab with Arduino by installing matching programme ,,,i normally do this with Labview