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Nephritis could happen with the patients.
It has huge adverse effect on Urinary system specially the Kidney Failure
kiney failure is the main side effect
Regular adjusted doses of NSAID are not harmful for the healthy kidneys, however, more frequent doses may induce renal function impairments. Adverse effect may extend from fluid retention, electrolyte irregularities (hyperkalemia) to more sever effects as Nephrotic syndrome with interstitial nephritis (Rare) or Papillary necrosis (very rare).
Rational prescribing and dispensing with proper counseling, is the golden role to avoid of minimize NSAID ADRs.
Non steroidal anti inflammatory drugs may cause acute renal failure by inhibation of prostaglandins synthesis.
NSAIDs may cause acute renal failure by inhibation of synthesis of prostaglandins.
long term use of NSAIDS may cause acute renal failure and cause reduction of renal prostaglandins i n patients
