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what is the indication for surfactant adminstration
premature labour and delivery
Pulmonary surfactant is a complex mixture of phospholipids and proteins that serves to reduce alveolar surface tension. It is formed by type II pneumocytes from about 20 weeks of gestation. Surfactant creates a continuously reforming surface layer over the alveoli which reduces surface tension, prevents atelectasis and maintains alveolar stability. A deficiency or dysfunction in pulmonary surfactant production causes Respiratory Distress Syndrome (RDS). Risk factors associated with RDS are shown in Table 1, and incidence of RDS at RPA 1992-8 in Figure 1. Exogenous surfactant has been shown to reduce neonatal mortality, death or bronchopulmonary dysplasia (BPD) and airleaks
All Neonates 29 to 32 weeks( Rescue treatment) - If need intubation for respiratory distress - do it- BEST - But mortality with RD not changed if no surfactant deficiency
surfactant is indicatedin premature babies where their lungs are not completely matured enough..administering surfactant improve the maturity of the lungs ..usually it is administered within 24hrs after birth foe better results
surfactant is used for preterm delivered newborn who are likely to develope respiratory distress syndrome dueRDS to low lecithin and surfactant. surfactant help inflating the lungs with air and avoid
this is use for new born that has problem with the respiratory system such as secnodary surfactant defieciency. If not administered it could lead to morbidity. while in the womb fetus only gets oxygenated blood form their mothers, if surfactant from the lungs is lesser than normal or not present at all,babies will have problem breathing.
Preterm deliveries with Respiratory Distress Syndrome (RDS).
surfactant keeps the alveolar open up and prevent their collapse ,this is in order to have a ,better better air exchange and better oxygenation
Surfactant decrease the alveolar fraction in the lungs.
The most common indication for surfactant administration is Hyaline membrane disease which is most commonly due to permaturity.
1)PREMATURITY WITH R.D
2)SEVER RD IN NEONATES
