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Because IS-IS is not solely an IP protocol, IS-IS can easily be used for other non-IP applications, such as for Layer 2 routing implementations like Cisco OTV, and Cisco FabricPath.
Intermediate System to Intermediate System (IS-IS) is a routing protocol designed to move information efficiently within a computer network, a group of physically connected computers or similar devices. It accomplishes this by determining the best route for data through a packet-switched network.