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New Business can or cannot run by one person ?
I would rather say that one person can run a new business alone, another question is to develop it. For example, you created an online hand-made shop - can you deal with it alone? With enough free time and a laptop/computer/smartphone - of course. But if you want to open a physical shop in your city and keep maintaining online sales? Probably, you will need to hire a seller at least.
I would also like to share this research on starting a new e-business - it includes the process assessment, the main principles, opportunities. It just helps to understand the new business model we have nowadays.
Thus, answering your question again - you can run your business alone. But if you want to enter new markets or expand your offers - you need a team.