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Normally companies who has adopted integration using IBM WebSphere and Middleware technologies in their environment has tremendous amount of investment in terms of work hours and money. Going cloud for WebSphere Application Server will not be as hard and I will recommend that.
Going cloud for WebSphere Message Broker will not be easy as WebSphere Message Broker message flow or web service contains lots of technologies associate with it. For example, you might have scenario where .net based web service calling IMS transactions in mainframe. In this case you will have .net application might be running in windows environment, you might build a message flow or web service in WebSphere Message Broker, create message definition for xml wsdl and Cobol copybook. Do message transformation from xml to copybook and copybook to xml. Sent message to mainframe using WebSphere MQ, queue manager connection and queues, using MQ-IMS bridge hit IMS transactions and get the response back to internet browser where customer might be access his or her account will take very tedious amount of work to go cloud.
DataPower and IBM Business Process Manager will not be as complex.
