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A fibrinogen activity test is ordered
As part of an investigation of a possible bleeding disorder or thrombotic episode.
As a follow-up to an abnormal Prothrombin Time (PT) or Partial Thromboplastin Time (PTT) and/or an episode of prolonged or unexplained bleeding.
It may be measured, along with tests such as PT, PTT, platelet function tests, fibrin degradation products (FDP), and D-dimer to help diagnose disseminated intravascular coagulation (DIC) or abnormal fibrinolysis. Occasionally, a fibrinogen activity test is ordered to help monitor the status of a progressive disease (such as liver disease) over time, or rarely, to monitor treatment of an acquired condition (such as DIC).
Fibrinogen -Low Prothrombin Time -Prolonged-------indicates hypofibrinogenaemia
Fibrinogen-Normal Prothrombin Time - Prolonged------ Indicates Higher Cascade Clot
anomaly.Need Individual Clotting
factor assay work up like50:50 Mix.
I have only stars in my mind now...... :)
As we know that thrombin is used to convert fibrinogen to fibrin to make a clott and is a qualitatve essay for fib.
while fibrinogen essay is a quantitative evaluation for fibrinogen which tells us the ammount presnt regardless of its funcion
