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While running out of physical GPU memory shouldn't be catastrophic in the blue-screen sense (GPU drivers are designed to adapt when storage demands outpace capacity), it's generally a performance killer. When it comes to GPU processing, executing out of local memory delivers performance that’s orders of magnitude higher than executing piecemeal out of system memory (i.e., multiple copies of data subsets to GPU memory) — and that will directly translate to a major slowdown in rendering throughput. Thus we can conclude that excess GPU size is not as such a performance issue but the lower the capacity of GPU we have than the demand of our applications then we will face performance degradation.