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Just try to learn @media quiries in the CSS and start building the designs from scratch because you will find it very easy.
Create Your won Css Media Quiries
The boot strap and other frameworks are collection of javascript libiaries desgined by experts and based on studies to fit all devices and cross browsers feature so if u want to giveup and undont want to use them u have to create ur owne libary
Yes you can, use can use your own ... @media queries in css, which is a css role section has a condition, will apply when the condition be true.