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Go to Tools Menu and then select Customize and then select edit custom files and then select program parameters acad.pgp file.
Acad.pgp File will be open in Notepad.
You can make your own shortcut for any command and safe. You can change also the existing shortcut as per your requirement but be sure you are expert in AutoCAD otherwise may maybe you lose some commands.
Use Command "Aliasedit" in the pop up window you can add/remove/edit shortcuts
Go to tool menu and press customise ,select edit ,then select programme parameters.
Also press command alias editor
go to ( express>tools>command alias editor ) you will find express after the help word in the main file bar
hope i got the question right :)
By editing the existing shortcut as per your requirement ,go to tools menu then customize then edit program parameter ( acad.pgp file) .after editing close and re-open autocad.