What are the Vitamin K Dependent Coagulation Factors ?

Vit K is essential for activity of several carboxylase enzymes within the hepatic cells,and therefore is necessary for the activation of coagulation factors VII,IX,X,II.These factors contain carboxyglutamic acid,which is carboxylated by gamma-glutamyl carboxylase. Vit K is the active coenzyme in this process,providing energy for the reaction through oxidation,after carboxylation,these proteins gain affinity for the negatively charged phospholipids on the surface of platelets and promote coagulation.

Factors are10,9,7,2. To be remembered easily it resembles year1972

Vit k dependent factors are II,VII, IX, X.