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patient was diagnosed as a case of pulmonary TB, ATT was started but he build up serum creatinine around7. Streptomycin and ethambutol was stopped but still he has raised creatinine level. how we further manage this patient regarding his antituberculous therapy.?
Streptomycin induced nephrotoxicity can be permanent. Adding a floroquinolono to the first line regimen instead of ethambutol is the option as the other first line ATT are not excreated via kidney
