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1. Let your customers communicate how they feel
2. Listen to your customers and their viewpoint of the problem.
3. Fix the problem at hand immediately.
Depends, really.
If by "tough" you mean angry, I feel the most effective way is to try and be as tactful and diplomatic as possible. Keep a level head, because they want to get it over with as quickly as possible too; nobody wants to deal with a problem any longer than they need to, and that includes the angry customer.
Don't be too aloof either though. Being diplomatic and letting the customer vent is one thing, but doing it to the extent that they feel you're not listening and just agreeing with what they say just so they stop will only worsen the situation.
Secondly, if by "tough", you mean a hard-sell, find their niche. Find what makes them tick. If you relate to them and make them feel comfortable, they'll open up to you without you having to even lift a finger. Once they realize you're trying to be on their side, they'll soften. And finally, don't give them the impression that you're selling to them purely for your own benefit. Make them feel they need whatever it is you're selling. Make them feel you're looking out for their best interests.
Best of luck to you, and I hope this helps!