What is the difference between Galileo and saber?

1. Market Share - In general Amadeus is the largest GDS however Amadeus is very weak in the US. Sabre is strong in the US and North America but weak everywhere else. Travelport owns both Galileo and Worldspan. Galileo is fast loosing marketshare but used to be large in Europe, Africa, the middle east and Asia. This is a well known picture of the three GDSs in airline groups. 
2. Founding Airlines - Sabre with American, Australian, JAL et al Amadeus - Lufthansa, Air France, Iberia, Continental Air, and Scandinavian. Travelport - Delta, British, KLM, SwissAir, Alitalia, etc. Worldspan and Galileo together.
3. Customer portals - The three GDS also have a customer portal for end-users. Sabre calls its portal as Virtually There, Amadeus as Check My Trip, while Travelport uses ViewTrip and My Trip and more.
4. PNR - Sabre PNRs are created with letters from alphabet. Amadeus however uses alpha-numerics. It might not seem significant but the permutations possible increases 7 times (from 26^6 to 36^6). I don't know about Travelport PNRs. 

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what are the difference between specific job & skills & general  job

The command entries are different from each other but concepts are the same.

In simple way difference Between both GDS is their command entries.

There are four major systems, known as Computer Reservations Systems (CRS) or if you use the new term, "Global Distribution Systems" (GDS). They are: 1. Sabre: Created by American Airlines; widely known as the most technologically advanced system. Used by most travel agents worldwide. 2. Apollo (Galileo): Created by United Airlines; integrated into the similar European Galileo system in the mid 90s. Also known as Covia.  These systems have different interfaces and entries, but all perform the same basic tasks: allow booking and ticketing of air segments allow booking of hotels and rental cars have extensive data pages concerning air carrier, hotel, and rental car company information and policies Major air carriers who use one particular system will tailor their partition of that GDS to their airline's needs, and also get the option of sophisticated yield management and inventory control systems within the GDS they use. U.S. Major Air Carriers and their Systems: American Airlines: Sabre Alaska Airlines: Sabre America West: System One Continental Airlines: System One Southwest: Sabre-based inhouse system United Airlines: Apollo US Airways: Sabre All of the systems "talk" to one another as well, which is how a carrier using Sabre can successfully make a reservation on a carrier that uses Apollo, or vice-versa. The exception is Southwest, which does not participate with other systems.  The thing to keep in mind is that getting a GDS is no different than buying a car. You and I could both get a Toyota Camry...but while yours was inexpensive and has no options, mine might be really expensive but has power everything, a sunroof, leather seats, etc. In other words, after airlines and travel agencies decide which GDS to go with, they can choose a wide variety of options and capabilities, purchased in a "package" from the GDS vendor.  So, the Sabre set used by an American Airlines agent will look different than one used by an Alaska Airlines agent or a US Airways one, since they all have different packages they've purchased. A trend of late from the agency community is to abandon the GDS entirely (and the expensive fees that come with subscribing) in favor of booking clients solely from each carrier's own website or through internet-based agencies like Orbitz, Travelocity, and Expedia. All the agency needs is a good PC with a fast internet connection, and they're set. They collect service fees from clients to do the bookings without the expense and hassle of subscribing to a GDS, keeping ticket stock on hand, etc.