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Answer to this Question is totally depends on Sales person and yes if he has done ground work, have understand customer "Sales Stage", "Nature of Customer Need", "Budget availability", "Competitive Position" then he can easily conclude the probability.
Before we offer to customer, we should find out customer's requirement and exactly what he/she wants. Based on it we will come to know the customer will buy or not before, we finish the meeting.
FRIST TIME WE FINISH THE MEETING
There is always an indication if the client we are meeting with is postive or not. What normally matters to them the most are the prices and the time frame. Howver, everything can be worked out and though there are clients who seemed not so much interested, with proper explaination and consistent follow-up, they can be converted into sales.