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For which hematological malignancy are non-cryopreserved stem cells most suitable and why?

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Question ajoutée par Khalid Al-Anazi , Chairman of Hematology Department and Director of Stem Cell Transplantation , King fahad Specialist Hospital
Date de publication: 2016/09/27
Afeefa P A
par Afeefa P A , Medical Laboratory Technologist , Modern Diagnostic Centre

Non-cryopreserved peripheral blood stem cells autotransplants for hematological malignancies can be performed entirely on an outpatient basis

 

The use of noncryopreserved stem cells in transplantation has the following advantages: 

(1) simplicity of implementation and allowing auto-HSCT to be done entirely as outpatient

(2) reduction of transplant costs

(3) expansion of the number of medical institutions that offer stem cell therapy

(4) prevention of DMSO toxicity

(5) saving time between the last induction therapy and high-dose therapy

(6) no significant reduction in viability of collected stem cells provided infusion is done within 5 days of collection. 

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