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Non-cryopreserved peripheral blood stem cells autotransplants for hematological malignancies can be performed entirely on an outpatient basis
The use of noncryopreserved stem cells in transplantation has the following advantages:
(1) simplicity of implementation and allowing auto-HSCT to be done entirely as outpatient
(2) reduction of transplant costs
(3) expansion of the number of medical institutions that offer stem cell therapy
(4) prevention of DMSO toxicity
(5) saving time between the last induction therapy and high-dose therapy
(6) no significant reduction in viability of collected stem cells provided infusion is done within 5 days of collection.