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What medications are best for the treatment of asthma? What are their side effects?

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Question ajoutée par Mounia Adel , Communications Officer , Etisalat
Date de publication: 2017/07/17
Andjelka Stojkovic
par Andjelka Stojkovic , Head of Department for pulmonology, allergology and cardiology , Clinical Centre, Paediatric Clinic

The better known choice for possible control of asthma are antiinflammatory drugs as inhaled corticosteroids (ICS) and leukotriene modifiers (ALT). But, the choice is dependent of asthma phenotype. For mild and moderate asthma the most use drugs are ICS and ALT. For severe asthma, beside mentioned often is necessary to use high dose of ICS, some systemic steroids and a higher dose of long-acting beta agonists and slow realise theophylline and long acting muscarin receptor antagonist and some biological drugs. 

Generally looking, inhaled steroids has possible harm effect with dose higher than 400 mcg accounted to beclomethason dipropionate (BDP) and stronger adverse effect if the dose is higher than 750-800 mcg accounted to BDP and the sure adverse effect if dose is higher than 1600 mcg accounted to BDP. During two decades of postmarketing observation, the leukotriene modifiers showed strong adverse effect if child use higher dose than prescribed and during poisoning. The less adverse effect showed leukotriene receptor antagonists than leukotriene synthesis inhibitors. 

The most important side effects of inhaled are failure in growth and negative effect on the pituitary axis - hypothalamus. The mild side effects are thrush and hoarsness. Systemic steroids have much side effects as: weakness, acne, weight gain, mood or behavior changes, upset stomatch, bone loss, eye changes, slowing of growth. 

The most obvious side effects of leukotriene modifiers (ALT) are: headache, nausea, vomiting, insomnia, irritability and these are expressive when ALT interfere with some medications (blood thinners, antiepileptics). 

 

Mohammed Rafiqul Islam
par Mohammed Rafiqul Islam , HSE Officer , Production Servicer Network

 

Keep up routine check especially lung and heart.

 

Observe doctor advice.

 

So far my knowledge, it is dust related problem.

 

Look and live in fresh air and avoid dust.

 

Use respiratory aids, where required.

 

 

mehdi haddad
par mehdi haddad , owner , haddad mehdi physitheraptic center

Corticosteroids + Selective beta2-adrenergic agonists for inhalation

 

These undesirable effects are in a very large majority of non-serious cases (eg difficulty in finding sleep)

 

insomnia, increased appetite

Edin Jusufovic
par Edin Jusufovic , Pulmonologist , Centre For Pulmonary Diseases Of Health And Educational Institution Tuzla

Inhaled corticosteroids with or without bronchodilatatorsSide effects: dry mouth, fungal infections in mouth; less common osteporosis

Shadi Faour
par Shadi Faour , Qualified Family Doctor , Jordanian MOH

management based on asthma severity.The management of the disease requires determining the age and symptoms of patient with observation

Etinosa Nehizena
par Etinosa Nehizena , Leader , Touching lives international

The main types of anti-inflammatory drugs for better asthma control are steroids or corticosteroids. Other anti-inflammatory treatments include leukotriene modifiers and immunomodulators. The effect of these drugs are minimal because doctors will prescribe it at low dose Inhaled steroids have fewside effects, especially at lower doses.Thrush(ayeast infectionin themouth) and hoarseness may occur, although this is rare. Rinsingthemouth, gargling after using the asthma inhaler, and using a spacer device with metered dose inhalers can help prevent these side effects. Thrush is easily treated with a prescriptionantifungallozenge or rinse. Inhaled steroids (asthma inhalers) are safe for adults and children. Side effects with these anti-inflammatory asthma inhalers are minimal. Your doctor will prescribe the lowest dose that effectively controls your child's or your asthma. On a side note, many parents are concerned about giving their children "steroids." Inhaled steroids arenotthe same asanabolic steroidsthat some athletes take to build muscle. These steroids are anti-inflammatory drugs, the cornerstone of asthma therapy. There are many benefits of using anti-inflammatory asthma inhalers tomanage asthma. Benefits : The benefits of inhaled steroids for better asthma control far exceed their risks, and include: Reduced frequency of asthma attacksDecreased use of beta-agonist bronchodilators (quick relief or rescue inhalers)ImprovedlungfunctionReduced emergency room visits and hospitalizations for life-threatening asthma

Morgana Costa de  Melo Lubbad
par Morgana Costa de Melo Lubbad , Chief Physiotherapy and Health Auditor , CPM BRASIL IMPORT AND EXPORT COMMODITIES LTDA.

Initially, is calming down. After that, we have a group of medication that all will depend on the state of the patient. In some cases, we could initiate with an antiallergic medication, so as to immediately after start giving him oxygen with Ipratropium bromide and Fenoterol mixture. 

If the case is more complex, we are not doctors, we should by now have his assistance and act accordingly. After the status of the patient is stabilized we need to discover what took him to this point. So as to avoid, and later create the correct treatment, muscular and respiratory. 

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