In Blood Banking, donor blood is tested for specific transmissible diseases and pathogenic agents. For what should we test for? And Why?

AIDS------HIV-I,II, PCR

Hepatitis A virus-------HAV Ab

Hepatitis B virus ------ HBs Ag, HBc IgM, PCR

Hepatitis C virus----- HCV Ab ,  PCR

Cytomegalovirus ----CMV-I,II

T-Lymphotropic Virus (HTLV I/II)

 Malaria, Leishmaniasis, Syphilis,

we essentially test for Hepatitis and Human Immunodeficiency virus(HIV). Because the presence of both in blood result in the transmission of such a deadly viruses to the normal patient.

Hepatitis

Syphilis

Malarial Parasite

HIV

HBSAG

VDRL

MALARIA

HGB/ HCT

HIV

THIS IS THE ONE ROUTINELY CHECK OR SCREENING IN BLOOD DONATION

Human Immunodeficiency virus, hepatitis B and C, Malarial parasite, Syphillis.

Basically to avoid "tti" transfusion transmissible infection and they include hepatitis, HIV etc

HIV,HBV,HCV,VDRL,MALARIA

THESE TESTS ARE DONE BECAUSE THESE DISEASES CAN BE TRANSMITTED BY BLOOD PRODUCTS 

HIV, HBsAg, HCV, VDRL AND MALARIA ALL THESE TEST ARE MANDATORY IN BLOOD BANK FOR Avoid infection before Blood Transfusion

*In blood bank always the donor is screening to donate save blood component which is free of any agent that can be harmful to the recipient .

*So always the blood is screening for all blood transmitted disease .

* And this transfusion transmitted disease is depended in the location endemic  for that particular disease.

*Some country  blood bank have there policies to screening  for specific transmitted disease but in general the major one is:

1-HIV

2-HCV

3-HbAgs

4- VDRL

5- Malaria.

6- Ctyo-megalo virus(CMV )

7-Human T-Lymphotropic Virus.

8- Chagas disease.

9- Leishmaniasis. 

10- West Nile Virus

the blood is tested for all the above pathogens. and they are tested so no disease would be transmitted to the recipient.

However, donors blood is not just tested for the presence of pathogens, it is also tested for the presence of anti-bodies that could be transmitted to the recipient. For example if you transmit a blood that contain crtain antibody and the patient might have the corresponding antigen, then that will cause haemolytic anaemia. That is why it is very crucial to cross match the blood between recipeints and donors before the transfusion if it is possible. If the patient in the emergency department and no time to cross match, then the scientist will dispatch O negative blood, and in the mean while will contiue the regular testing. the patient should be monitored closely for any signs of jaundice, hyperventilation, fatigue. open IV lines are to be maintained and kidney function is monitored as well

The donor's blood unit is tested for the following:

1. Viruses: HIV, Hepatitis A, Hepatitis B, Hepatitis C, Human T-Lymphotropic Virus (HTLV I/II), Cytomegalovirus (CMV), West Nile Virus, Simian foamy virus (SFV), SARS

2. Parasites and specific bacteria: Malaria (Plasmodia spp.), Babesiosis, Chagas disease, Leishmaniasis, Syphilis, Lyme disease

3. Other bacteria: Skin flora, Bacteremia and platelets