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The U.S. Environmental Protection Agency (USEPA) method detection limit (MDL) is described as the minimum concentration of a substance that can be measured and reported with99-percent confidence that the analyte concentration is greater than zero (U.S. Environmental Protection Agency,1997) and is based on the approach of Glaser and others (1981). The MDL protects against incorrectly reporting the presence of a compound at low concentrations in cases when noise and actual analyte signal may be indistinguishable. The MDL concentration does not imply accuracy or precision of the quantitative measurement.
